Article
Molecular genetic studies of DMT1 on 12q in French-Canadian restless legs syndrome patients and families.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2007
Xiong Lan, Dion Patrick, Montplaisir Jacques, Levchenko Anastasia, Thibodeau Pascale, Karemera Liliane, Rivière Jean-Baptiste, St-Onge Judith, Gaspar Claudia, Dubé Marie-Pierre, Desautels Alex, Turecki Gustavo, Rouleau Guy A
Abstract excerpt
Converging evidence from clinical observations, brain imaging and pathological findings strongly indicate impaired brain iron regulation in restless legs syndrome (RLS). Animal models with mutation in (DMT1) divalent metal transporter 1 gene, an important brain iron transporter, demonstrate a sim...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.