Article
A potential role for zinc in restless legs syndrome.
Sleep - 9 Apr 2021
Chen Pan, Bornhorst Julia, Patton Stephanie, Bagai Kanika, Nitin Rachana, Miah Mahfuzur, Hare Dominic J, Kysenius Kai, Crouch Peter J, Xiong Lan, Rouleau Guy A, Schwerdtle Tanja, Connor James, Aschner Michael, Bowman Aaron B, Walters Arthur S
Abstract excerpt
STUDY OBJECTIVES: Evaluate serum and brain noniron metals in the pathology and genetics of restless legs syndrome (RLS). METHODS: In two independent studies (cohorts 1 and 2), in which subjects either remained on medications or tapered off medications, we analyzed serum levels of iron, calcium, magnesium, manganese, copper, and zinc both in RLS patients and controls, and assessed the prevalence of the MEIS1 and...
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