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Article

ND4 mutation in transitional cell carcinoma: Does mitochondrial mutation occur before tumorigenesis?

Mitochondrion - 1 Jul 2007

Tzen Chin-Yuan, Mau Bey-Liing, Wu Tsu-Yen

Abstract excerpt

To investigate how mitochondrial mutation occurs in cancers, we analyzed ND4 mutation in 53 transitional cell carcinomas (TCCs) of the upper urinary tract and the normal counterpart (perirenal soft tissue). Three methods, i.e., DNA sequencing, restriction fragment length polymorphism (RFLP), and denaturing high-performance liquid chromatography (DHPLC), were employed because of their different sensitive of...

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PMID: 17509949
DOI: 10.1016/j.mito.2007.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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