Number of nevi and early-life ambient UV exposure are associated with BRAF-mutant melanoma.

doi:10.1158/1055-9965.EPI-06-1038

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Article

Number of nevi and early-life ambient UV exposure are associated with BRAF-mutant melanoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2007

Thomas Nancy E, Edmiston Sharon N, Alexander Audrey, Millikan Robert C, Groben Pamela A, Hao Honglin, Tolbert Dawn, Berwick Marianne, Busam Klaus, Begg Colin B, Mattingly Dianne, Ollila David W, Tse Chiu Kit, Hummer Amanda, Lee-Taylor Julia, Conway Kathleen

Abstract excerpt

Malignant melanomas often contain BRAF or NRAS mutations, but the relationship of these mutations to ambient UV exposure in combination with phenotypic characteristics is unknown. In a population-based case series from North Carolina, 214 first primary invasive melanoma patients in the year 2000 were interviewed regarding their risk factors. Ambient solar UV exposures were estimated using residential histories...

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Identifiers

PMID: 17507627
DOI: 10.1158/1055-9965.EPI-06-1038

Genes

BRAF
NRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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