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Article

X chromosome transmission ratio distortion in Cftr +/- intercross-derived mice.

BMC genetics - 16 May 2007

Haston Christina K, Humes Daryl G, Lafleur Melanie

Abstract excerpt

BACKGROUND: Cystic fibrosis (CF) mice, created with a genetically engineered mutation in the Cystic fibrosis transmembrane conductance regulator (Cftr) gene, may develop intestinal plugs which limit their survival past weaning. In a studied population of genetically mixed CF mice differences in allelic ratios at particular loci, between surviving CF mice and mice with the lethal intestinal defect, were used to...

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Identifiers

PMID: 17506901
DOI: 10.1186/1471-2156-8-23
PMCID: PMC1885815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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