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Article

Racial differences in CYP3A4 genotype and survival among men treated on Radiation Therapy Oncology Group (RTOG) 9202: a phase III randomized trial.

International journal of radiation oncology, biology, physics - 1 Sept 2007

Roach Mack, De Silvio Michelle, Rebbick Timothy, Grignon David, Rotman Marvin, Wolkov Harvey, Fisher Barbara, Hanks Gerald, Shipley William U, Pollack Alan, Sandler Howard, Watkins-Bruner Deborah

Abstract excerpt

PURPOSE: Inherited genotypes may explain the inferior outcomes of African American (AA) men with prostate cancer. To understand how variation in CYP3A4 correlated with outcomes, a retrospective examination of the CYP3A4 *1B genotype was performed on men treated with Radiation Therapy Oncology Group (RTOG) 92-02. METHODS AND MATERIALS: From 1,514 cases, we evaluated 56 (28.4%) of 197 AA and 54 (4.3%) of 1,274...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17498886
DOI: 10.1016/j.ijrobp.2007.03.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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