Article
Influence of GSTM1 genotype on association between aromatic DNA adducts and urinary PAH metabolites in incineration workers.
Mutation research - 15 Feb 2002
Lee Jeongmi, Kang Daehee, Lee Kyoung-Ho, Ichiba Masayoshi, Zhang Jiusong, Tomokuni Katsumaro, Hwang Eung Soo, Park Chung-Gyu, Ha Mina, Kim SungGyun, Han Sang-Beom, Choi Jae Wook, Lee Eunil, Jang Jae-yeon, Strickland Paul T, Hirvonen Ari, Cho Soo-Hun
Abstract excerpt
Waste incinerating workers are exposed to various pyrolysis products including polycyclic aromatic hydrocarbons (PAHs). We examined their PAH exposure by assessing urinary 1-hydroxypyrene glucuronide (1-OHPG), as a measure of internal dose, and aromatic DNA adducts in peripheral white blood cells (WBCs), as a measure of biological effect dose. The potential effect of genetic polymorphisms of three enzymes...
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