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Adult marrow-derived very small embryonic-like stem cells and tissue engineering

1 Oct 2007

Abstract excerpt

A population of CXCR4(+) lin(-) CD45(-) cells that express SSEA, Oct-4 and Nanog has been identified in adult bone marrow. These cells are very small and display several features typical for primary embryonic stem cells such as: i) a large nuclei surrounded by a narrow rim of cytoplasm; ii) open-type chromatin (euchromatin); and iii) high telomerase activity. These cells were named very small embryonic-like stem...

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PMID: 17916043
DOI: 10.1517/14712598.7.10.1499

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