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Article

Inferring purging from pedigree data.

Evolution; international journal of organic evolution - 1 May 2007

Gulisija Davorka, Crow James F

Abstract excerpt

The harmful effects of inbreeding can be reduced if deleterious recessive alleles were removed (purged) by selection against homozygotes in earlier generations. If only a few generations are involved, purging is due almost entirely to recessive alleles that reduce fitness to near zero. In this case the amount of purging and allele frequency change can be inferred approximately from pedigree data alone and are...

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Identifiers

PMID: 17492959
DOI: 10.1111/j.1558-5646.2007.00088.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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