Alpha 1-antitrypsin deficiency and liver disease: clinical presentation, diagnosis and treatment.

doi:10.1007/BF01797920

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Article

Alpha 1-antitrypsin deficiency and liver disease: clinical presentation, diagnosis and treatment.

Journal of inherited metabolic disease - 1 Jan 1991

Hussain M, Mieli-Vergani G, Mowat A P

Abstract excerpt

The alpha 1-antitrypsin deficient subject (protease inhibitor (PI) phenotype ZZ) has an increased susceptibility to liver disease. The condition is most commonly identified in early infancy as a conjugated hyperbilirubinaemia with hepatitis (11%) or a bleeding state due to vitamin K malabsorption...

Topics

Humans
Liver Diseases
Phenotype
alpha 1-Antitrypsin Deficiency

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