Developmental plasticity and developmental origins of non-communicable disease: theoretical considerations and epigenetic mechanisms.

doi:10.1016/j.pbiomolbio.2010.12.008

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Article

Developmental plasticity and developmental origins of non-communicable disease: theoretical considerations and epigenetic mechanisms.

Progress in biophysics and molecular biology - 1 Jul 2011

Hanson Mark, Godfrey Keith M, Lillycrop Karen A, Burdge Graham C, Gluckman Peter D

Abstract excerpt

There is now evidence that developmental influences have lifelong effects on cardiovascular and metabolic function and that elements of the heritable or familial component of susceptibility to cardiovascular disease, obesity and other non-communicable diseases (NCD) can be transmitted across generations by non-genomic means. In animals the developmental environment induces altered phenotypes through genetic,...

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Identifiers

PMID: 21219925
DOI: 10.1016/j.pbiomolbio.2010.12.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.