Article
The association of the beta1-tubulin Q43P polymorphism with intracerebral hemorrhage in men.
Haematologica - 1 Apr 2007
Navarro-Núñez Leyre, Lozano María L, Rivera José, Corral Javier, Roldán Vanessa, González-Conejero Rocío, Iniesta Juan A, Montaner Joan, Vicente Vicente, Martínez Constantino
Abstract excerpt
BACKGROUND AND OBJECTIVES: Platelets play a fundamental role in hemostasis and alterations of their function can be determinant in the onset of stroke. A polymorphism in beta1-tubulin (TUBB1 Q43P), a protein specifically expressed in the megakaryocytic line, has been described as a protective factor in cardiovascular disease. The potential effect of this variant in the pathogenesis of hemorrhagic stroke has not...
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