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Human Gammaherpesvirus 8 Oncogenes Associated with Kaposi’s Sarcoma

28 Jun 2022

Abstract excerpt

Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human gammaherpesvirus 8 (HHV-8), contains oncogenes and proteins that modulate various cellular functions, including proliferation, differentiation, survival, and apoptosis, and is integral to KSHV infection and oncogenicity. In this review, we describe the most important KSHV genes [ORF 73 (LANA), ORF 72 (vCyclin), ORF 71 or ORFK13 (vFLIP), ORF 74...

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PMID: 35806208
DOI: 10.3390/ijms23137203

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