Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epilepsy in phenylketonuria: a complex dependence on serum phenylalanine levels.

Epilepsia - 1 Jun 2007

Martynyuk Anatoly E, Ucar Deniz A, Yang Dawn D, Norman Wendy M, Carney Paul R, Dennis Donn M, Laipis Philip J

Abstract excerpt

PURPOSE: Phenylketonuria (PKU) is a disorder of phenylalanine (Phe) metabolism that frequently results in epilepsy if a low Phe diet was not implemented at birth. The mechanisms by which Phe affects the brain are poorly understood. METHODS: Audiogenic seizures (AGS) were studied in female homozyg...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acoustic Stimulation
Share to Age Factors
Share to Circadian Rhythm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epilepsy

Share to Epilepsy, Reflex

Share to Mice, Mutant Strains

Share to Phenylalanine

Share to Phenylketonurias

Source

Identifiers

PMID: 17484755
DOI: 10.1111/j.1528-1167.2007.01115.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17484755-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epilepsy in phenylketonuria: a complex dependence on serum phenylalanine levels.PMID 17484755Read ↗

Early-onset behavioral and neurochemical deficits in the genetic mouse model of phenylketonuriaSemantic proximity Read ↗

Differential effects of low-phenylalanine protein sources on brain neurotransmitters and behavior in C57Bl/6-Pah(enu2) mice.Semantic proximity Read ↗

Experimental Animal Models of Phenylketonuria: Pros and ConsSemantic proximity Read ↗

Behavioral and neurochemical characterization of the spontaneous mutation tremor, a new mouse model of audiogenic seizures.Semantic proximity Read ↗

Genetically epilepsy-prone rats (GEPRs) and DBA/2 mice: Two animal models of audiogenic reflex epilepsy for the evaluation of new generation AEDs.Semantic proximity Read ↗

Behavioral Phenotyping of the Pahenu2 Mouse Model for Phenylketonuria-A Scoping Review and Future Perspectives.Semantic proximity Read ↗

The Behavioral Consequence of Phenylketonuria in Mice Depends on the Genetic BackgroundSemantic proximity Read ↗

The expression and phosphorylation of acid sensing ion channel 1a in the brain of a mouse model of phenylketonuria.Semantic proximity Read ↗

Breeding the phenylketonuria mouse: novel dietary regimen enables breeding of female C57BL/6J mice homozygous for the <i> Pah <sup>enu2</sup> </i> mutation without fosteringSemantic proximity Read ↗

The role of the inherited genetic background on the consequences of lithium-pilocarpine status epilepticus: study in Genetic Absence Epilepsy Rats from Strasbourg and Wistar audiogenic rats.Semantic proximity Read ↗

Of mice and men: Plasma phenylalanine reduction in PKU corrects neurotransmitter pathways in the brain.Semantic proximity Read ↗

Characterization of seizures in the flathead rat: a new genetic model of epilepsy in early postnatal development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.