Article
Increased production of pyruvic acid by Escherichia coli RNase G mutants in combination with cra mutations.
Applied microbiology and biotechnology - 1 Aug 2007
Sakai Taro, Nakamura Naoko, Umitsuki Genryou, Nagai Kazuo, Wachi Masaaki
Abstract excerpt
The Escherichia coli RNase G is known as an endoribonuclease responsible for the 5'-end maturation of 16S rRNA and degradation of several specific mRNAs such as adhE and eno mRNAs. In this study, we found that an RNase G mutant derived from the MC1061 strain did not grow on a glucose minimal medium. Genetic analysis revealed that simultaneous defects of cra and ilvIH, encoding a transcriptional regulator of...
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