Article
Attenuation of DNA damage checkpoint by PBK, a novel mitotic kinase, involves protein-protein interaction with tumor suppressor p53.
Biochemical and biophysical research communications - 22 Jun 2007
Nandi Asit K, Ford Tamara, Fleksher Daniel, Neuman Brian, Rapoport Aaron P
Abstract excerpt
Pathways adopted by developing cancer cells for evasion of cellular surveillance mechanism deserve attention for therapeutic exploitation as well as for better prognosis. A novel mitotic kinase, PDZ-binding kinase or PBK, which is upregulated in a variety of neoplasms including hematological mali...
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