Article
Translational control of SEPT9 isoforms is perturbed in disease.
Human molecular genetics - 1 Apr 2007
McDade Simon S, Hall Peter A, Russell S E Hilary
Abstract excerpt
A common feature of the mammalian septin gene family is complex genomic architecture with multiple alternate splice variants. Septin 9 has 18 distinct transcripts encoding 15 polypeptides, with two transcripts (SEPT9_v4 and v4*) encoding the same polypeptide. We have previously reported that the ratio of these distinct transcripts is altered in neoplasia, with the v4 transcript being the usual form in normal...
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