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Proteomic profiling of the oncogenic septin 9 reveals isoform‐specific interactions in breast cancer cells

19 Aug 2021

Abstract excerpt

Septins are a family of multimeric GTP-binding proteins, which are abnormally expressed in cancer. Septin 9 (SEPT9) is an essential and ubiquitously expressed septin with multiple isoforms, which have differential expression patterns and effects in breast cancer cells. It is unknown, however, if SEPT9 isoforms associate with different molecular networks and functions. Here, we performed a proteomic screen in...

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PMID: 34409731
DOI: 10.1002/pmic.202100155

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