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Article

Factors affecting drug concentrations and QT interval during thioridazine therapy.

Clinical pharmacology and therapeutics - 1 Nov 2007

Thanacoody R H K, Daly A K, Reilly J G, Ferrier I N, Thomas S H L

Abstract excerpt

The objective of this study was to investigate factors affecting steady-state plasma concentrations of thioridazine. A cross-sectional study of patients receiving chronic thioridazine was employed. Common allelic variants of CYP2D6 and CYP2C19, as well as thioridazine and metabolite concentrations and QTc intervals, were determined. In 97 patients, dose-corrected plasma concentrations (C/Ds) of thioridazine and...

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Identifiers

PMID: 17460606
DOI: 10.1038/sj.clpt.6100195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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