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Article

Mitochondrial DNA-deficient models and aging.

Annals of the New York Academy of Sciences - 1 Apr 2007

Olgun Abdullah, Akman Serif

Abstract excerpt

Human mitochondrial DNA (mtDNA) encodes 13 subunits of oxidative phosphorylation (OXPHOS) enzyme complexes I, III, IV, and V except complex II. MtDNA is more sensitive to oxidative damage than nuclear DNA. MtDNA defects are involved in many pathologies including aging. Several mtDNA-deficient cel...

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PMID: 17460185
DOI: 10.1196/annals.1395.025

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DHODH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17460185-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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