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Article

Peroxisome proliferator-activated receptor expression is reduced in skeletal muscle in COPD.

The European respiratory journal - 1 Aug 2007

Remels A H, Schrauwen P, Broekhuizen R, Willems J, Kersten S, Gosker H R, Schols A M

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a multiorgan systemic disease. The systemic features are skeletal muscle weakness and cachexia, the latter being associated with systemic inflammation. The exact mechanisms underlying skeletal muscle dysfunction in COPD remain obscure. Recent evidence suggests involvement of the peroxisome proliferator-activated receptors (PPARs) and PPAR-gamma coactivator...

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Source

Identifiers

PMID: 17459894
DOI: 10.1183/09031936.00144106

Genes

TFAM
PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Peroxisome proliferator-activated receptor expression is reduced in skeletal muscle in COPD.PMID 17459894Read ↗

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