Article
Possible mechanisms underlying the development of cachexia in COPD.
The European respiratory journal - 1 Mar 2008
Wagner P D
Abstract excerpt
About 25% of patients with chronic obstructive pulmonary disease (COPD) will develop cachexia (fat-free body mass index <17 kg.m(-2) (males) or <14 kg.m(-2) (females)). This is associated with approximately 50% reduction in median survival. The pathogenetic mechanism has been variously suggested to result from the following: 1) energy imbalance; 2) disuse atrophy; 3) tissue hypoxia from arterial hypoxaemia; 4)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.