Protection of yeast lacking the Ure2 protein against the toxicity of heavy metals and hydroperoxides by antioxidants.

Abstract excerpt

The aim of this study was to examine the protection of the yeast lacking the "antioxidant-like" prion precursor protein (Ure2p), by antioxidants and to elucidate how modification of redox homeostasis affects toxicity of agents inducing oxidative stress in the Deltaure2 cells. We found a diverse ability of a range of antioxidants to ameliorate the hypersensitivity of the Deltaure2 disruptant to oxidants and heavy...

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