Article
Association of apolipoprotein E polymorphism with age-related macular degeneration and Alzheimer's disease in south-western Hungary.
Ideggyogyaszati szemle - 30 Mar 2007
Kovács Katalin A, Pámer Zsuzsanna, Kovács Attila, Fekete Sándor, Miseta Attila, Kovács Bálint, Kovács Gábor L
Abstract excerpt
BACKGROUND: Age-related macular degeneration (AMD) and Alzheimer dementia (AD) show similarities (advanced age, formation of deposits of similar content). Recently apolipoprotein E 2 (apoE 2) has been associated with AMD, while apoE4 with AD. The question of coexistence, especially with respect to the genetic background has not been studied earlier. We investigated, therefore, the occurrence of AMD in AD patients...
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