Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prematurely aged children: molecular alterations leading to Hutchinson-Gilford progeria and Werner syndromes.

Current aging science - 1 Dec 2008

Domínguez-Gerpe Lourdes, Araújo-Vilar David

Abstract excerpt

Ageing is thought to be a polygenic and stochastic process in which multiple mechanisms operate at the same time. At the level of the individual organism ageing is associated with a progressive deterioration of health and quality of life, sharing common features such as: alopecia and grey hair, loss of audition, macular degeneration, neurodegeneration, cardiovascular diseases, osteoporosis, cataract formation,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Exodeoxyribonucleases
Share to Lamin Type A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Biological

Share to Progeria

Share to RecQ Helicases

Share to Werner Syndrome

Share to Werner Syndrome Helicase

Source

Identifiers

PMID: 20021393
DOI: 10.2174/1874609810801030202

Genes

LMNA
WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prematurely aged children: molecular alterations leading to Hutchinson-Gilford progeria and Werner syndromes.PMID 20021393Read ↗

Pathophysiology of premature aging characteristics in Mendelian progeroid disorders.Semantic proximity Read ↗

Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases.Semantic proximity Read ↗

Premature aging syndromes: From patients to mechanism.Semantic proximity Read ↗

Premature aging disorders: A clinical and genetic compendium.Semantic proximity Read ↗

Progeria: a rare genetic premature ageing disorder.Semantic proximity Read ↗

Hutchinson-Gilford Progeria Syndrome: A Premature Aging Disease.Semantic proximity Read ↗

The genetics of human ageing.Semantic proximity Read ↗

Mini-Review: molecular elucidations of hutchinson-gilford progeria syndrome: A hope for managing horrors of premature aging in children.Semantic proximity Read ↗

Towards delineating the chain of events that cause premature senescence in the accelerated aging syndrome Hutchinson-Gilford progeria (HGPS).Semantic proximity Read ↗

Genetics of aging, progeria and lamin disorders.Semantic proximity Read ↗

What can progeroid syndromes tell us about human aging?Semantic proximity Read ↗

Search and insights into novel genetic alterations leading to classical and atypical Werner syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.