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Article

MMP-2, MMP-9 and TIMP-2 gene polymorphisms in Chinese patients with generalized aggressive periodontitis.

Journal of clinical periodontology - 1 May 2007

Chen Dong, Wang Qi, Ma Zhi-Wei, Chen Fa-Ming, Chen Yue, Xie Guang-Yuan, Wang Qin-Tao, Wu Zhi-Fen

Abstract excerpt

BACKGROUND: Aggressive periodontitis (AgP) has a genetic basis. It has been reported that the functional gene polymorphisms of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase-2 (TIMP-2) alter their expressions in transcriptional level and they are involved in the tissue destruction of periodontitis. The study was carried out to analyse the association of functional polymorphisms...

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Source

Identifiers

PMID: 17448043
DOI: 10.1111/j.1600-051X.2007.01071.x

Genes

TIMP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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