Article
MMP-8 -799 C>T genetic polymorphism is associated with the susceptibility to chronic and aggressive periodontitis in Taiwanese.
Journal of clinical periodontology - 1 Dec 2011
Chou Yu-Hsiang, Ho Ya-Ping, Lin Ying-Chu, Hu Kai-Fang, Yang Yi-Hsin, Ho Kun-Yen, Wu Yi-Min, Hsi Edward, Tsai Chi-Cheng
Abstract excerpt
AIM: Matrix metalloproteinase (MMP)-8 is a protease that degrades numerous extracellular molecules and has been implicated in the pathogenesis of periodontitis. Polymorphism in the MMP-8 could affect the susceptibility to disease. Our aim was to evaluate the association between periodontitis and MMP-8 -799 C>T polymorphism. MATERIAL AND METHODS: Genomic DNA was obtained from 361 chronic periodontitis patients...
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