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Article

Dlk1/FA1 is a novel endocrine regulator of bone and fat mass and its serum level is modulated by growth hormone.

Endocrinology - 1 Jul 2007

Abdallah Basem M, Ding Ming, Jensen Charlotte H, Ditzel Nicholas, Flyvbjerg Allan, Jensen Thomas G, Dagnaes-Hansen Frederik, Gasser Jürg A, Kassem Moustapha

Abstract excerpt

Fat and bone metabolism are two linked processes regulated by several hormonal factors. Fetal antigen 1 (FA1) is the soluble form of dlk1 (delta-like 1), which is a member of the Notch-Delta family. We previously identified FA1 as a negative regulator of bone marrow mesenchymal stem cell differentiation. Here, we studied the effects of circulating FA1 on fat and bone mass in vivo by generating mice expressing...

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Identifiers

PMID: 17446189
DOI: 10.1210/en.2007-0171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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