Article
Killer cell immunoglobulin-like receptor polymorphisms in HLA-identical kidney transplant recipients: lack of 2DL2 and 2DS2 may be associated with poor graft function.
Tissue antigens - 1 Apr 2007
Cirocco R E, Mathew J M, Burke G W, Esquenazi V, Miller J
Abstract excerpt
Killer cell immunoglobulin-like receptors (KIR) on natural killer cells mediate killing by recognizing class I presentation of peptides by infected or oncogenic cells. KIR differences in stem cell transplants have been implicated in increased graft vs host disease. Human leukocyte antigen (HLA)-matched-related kidney recipients have the best graft survival as compared to one haplotype-matched recipients. These...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
