Article
Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.
Rheumatology (Oxford, England) - 1 Jul 2010
Kimoto Yasutaka, Horiuchi Takahiko, Tsukamoto Hiroshi, Kiyohara Chikako, Mitoma Hiroki, Uchino Ayumi, Furugo Isao, Yoshizawa Seiji, Ueda Akira, Harashima Shinichi, Sawabe Takuya, Tahira Tomoko, Hayashi Kenshi, Yoshizawa Shigeru, Shimoda Terufumi, Akashi Koichi, Harada Mine
Abstract excerpt
OBJECTIVE: Identification of the association of killer cell immunoglobulin-like receptor (KIR) genes with SLE and accompanying infections. METHODS: Presence or absence of all 14 KIR genes was studied for association with SLE by case-control studies. A total of 417 SLE cases, 72 RA cases and 256 controls, all of Japanese descent, were enrolled. RESULTS: The carrier frequency of KIR2DL5 was significantly decreased...
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