Article
Sequence-based typing of HLA-DQA1: comprehensive approach showed molecular heterogeneity.
Tissue antigens - 1 Apr 2007
Voorter C E M, Lee K W, Smillie D, Tilanus M G J, van den Berg-Loonen E M
Abstract excerpt
Within the human leukocyte antigen-DQA1 workshop project the level of molecular heterogeneity of the DQA1 gene was investigated. An improved sequence-based typing protocol was used, enabling analysis of the complete coding sequence, comprising exons 1-4. The participating laboratories implemented the amplification and sequencing primers in their own sequence-based typing approach. The method proved to be...
Topics
- Alleles
- Gene Frequency
- Genetic Variation
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- Histocompatibility Testing
- Humans
- Korea
- Polymerase Chain Reaction
- Sequence Analysis, DNA
- White People