Article
The locus for bovine dilated cardiomyopathy maps to chromosome 18.
Animal genetics - 1 Jun 2007
Guziewicz K E, Owczarek-Lipska M, Küffer J, Schelling C, Tontis A, Denis C, Eggen A, Leeb T, Dolf G, Braunschweig M H
Abstract excerpt
Bovine dilated cardiomyopathy (BDCMP) is a severe and terminal disease of the heart muscle observed in Holstein-Friesian cattle over the last 30 years. There is strong evidence for an autosomal recessive mode of inheritance for BDCMP. The objective of this study was to genetically map BDCMP, with the ultimate goal of identifying the causative mutation. A whole-genome scan using 199 microsatellite markers and one...
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