Article
Multiple-pathway analysis of double-strand break repair mutations in Drosophila.
PLoS genetics - 13 Apr 2007
Johnson-Schlitz Dena M, Flores Carlos, Engels William R
Abstract excerpt
The analysis of double-strand break (DSB) repair is complicated by the existence of several pathways utilizing a large number of genes. Moreover, many of these genes have been shown to have multiple roles in DSB repair. To address this complexity we used a repair reporter construct designed to measure multiple repair outcomes simultaneously. This approach provides estimates of the relative usage of several DSB...
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