Article
Suppression of defective-sporulation phenotypes by mutations in transcription factor genes of Bacillus subtilis.
Biochimie - 1 Jan 2000
Ng C, Buchanan C, Leung A, Ginther C, Leighton T
Abstract excerpt
Mutations in the Bacillus subtilis major RNA polymerase sigma factor gene (rpoD/crsA47) and a sensory receiver gene (spoOA/rvtA11) are potent intergenic suppressors of several stage 0 sporulation mutations (spoOB, OE, OF & OK). We show here that these suppressors also rescue temperature-sensitive sporulation phenotypes (Spots) caused by mutations in RNA polymerase, ribosomal protein, and protein synthesis...
Topics
- Bacillus subtilis
- Bacterial Proteins
- Carrier Proteins
- Flagellin
- Genes, Bacterial
- Hexosyltransferases
- Muramoylpentapeptide Carboxypeptidase
- Mutation
- Penicillin-Binding Proteins
- Peptidyl Transferases
- Phenotype