Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<i>Borrelia burgdorferi</i>Binding of Host Complement Regulator Factor H Is Not Required for Efficient Mammalian Infection

10 Apr 2007

Abstract excerpt

The causative agent of Lyme disease, Borrelia burgdorferi, is naturally resistant to its host's alternative pathway of complement-mediated killing. Several different borrelial outer surface proteins have been identified as being able to bind host factor H, a regulator of the alternative pathway, leading to a hypothesis that such binding is important for borrelial resistance to complement. To test this hypothesis,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Vector-Borne Animal Diseases
Share to Vector-borne infectious diseases
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17420242
DOI: 10.1128/iai.01923-06

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<i>Borrelia burgdorferi</i>Binding of Host Complement Regulator Factor H Is Not Required for Efficient Mammalian InfectionPMID 17420242Read ↗

Differential Binding of Host Complement Inhibitor Factor H by<i>Borrelia burgdorferi</i>Erp Surface Proteins: a Possible Mechanism Underlying the Expansive Host Range of Lyme Disease SpirochetesSemantic proximity Read ↗

Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmissionSemantic proximity Read ↗

Contribution of the Infection-Associated Complement Regulator-Acquiring Surface Protein 4 (ErpC) to Complement Resistance of<i>Borrelia burgdorferi</i>Semantic proximity Read ↗

Complement Inhibitor Factor H Binding to Lyme Disease Spirochetes Is Mediated by Inducible Expression of Multiple Plasmid-Encoded Outer Surface Protein E ParalogsSemantic proximity Read ↗

Complement therapeutic Factor H-IgG proteins as pre-exposure prophylaxes against Lyme borreliae infectionsSemantic proximity Read ↗

The Complement Regulator Factor H Binds to the Surface Protein OspE of Borrelia burgdorferiSemantic proximity Read ↗

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse fliesSemantic proximity Read ↗

Blood treatment of Lyme borreliae demonstrates the mechanism of CspZ ‐mediated complement evasion to promote systemic infection in vertebrate hostsSemantic proximity Read ↗

BGA66 and BGA71 facilitate complement resistance of <i>Borrelia bavariensis</i> by inhibiting assembly of the membrane attack complexSemantic proximity Read ↗

Serum resistance of<i>Acinetobacter baumannii</i>through the binding of factor H to outer membrane proteinsSemantic proximity Read ↗

Immune evasion of <i>Borrelia burgdorferi</i>: mapping of a complement‐inhibitor factor H‐binding site of BbCRASP‐3, a novel member of the Erp protein familySemantic proximity Read ↗

Host recognition and target differentiation by factor H, a regulator of the alternative pathway of complementSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.