Article
hOGG1 Ser326Cys polymorphism and susceptibility to gallbladder cancer in a Chinese population.
International journal of cancer - 1 Aug 2007
Jiao Xingyuan, Huang Jiefu, Wu Shengli, Lv Mingde, Hu Yize, Jianfu, Su Xiaokang, Luo Canqiao, Ce Broelsch
Abstract excerpt
The human oxoguanine glycosylase 1(hOGG1) gene encodes a DNA glycosylase that is involved in excision repair of 8-OH-dG (8-hydroxy-2-deoxyguanine) from oxidatively-damaged DNA. To determine whether hOGG1 plays a role in the risk for adenocarcinoma of the gallbladder, we tested the association of...
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