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Article

Meta-analysis of BRCA1 and BRCA2 penetrance.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Apr 2007

Chen Sining, Parmigiani Giovanni

Abstract excerpt

PURPOSE: Genetic counseling is now routinely offered to individuals at high risk of carrying a BRCA1 or BRCA2 mutation. Risk prediction provided by the counselor requires reliable estimates of the mutation penetrance. Such penetrance has been investigated by studies worldwide. The reported estima...

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Share to Breast Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 17416853
DOI: 10.1200/JCO.2006.09.1066
PMCID: PMC2267287

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17416853-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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