Article
Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis.
Experimental cell research - 1 May 2007
Kobayashi Shinta, Tanaka Atsushi, Fujiki Yukio
Abstract excerpt
Dynamin-like protein 1 (DLP1) and Pex11pbeta function in morphogenesis of peroxisomes. In the present work, we investigated whether Fis1 is involved in fission of peroxisomes. Endogenous Fis1 was morphologically detected in peroxisomes as well as mitochondria in wild-type CHO-K1 and DLP1-defective ZP121 cells. Subcellular fractionation studies also revealed the presence of Fis1 in peroxisomes. Peroxisomal Fis1...
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