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Article

Failure of microtubule-mediated peroxisome division and trafficking in disorders with reduced peroxisome abundance.

Journal of cell science - 15 Feb 2006

Nguyen Tam, Bjorkman Jonas, Paton Barbara C, Crane Denis I

Abstract excerpt

In contrast to peroxisomes in normal cells, remnant peroxisomes in cultured skin fibroblasts from a subset of the clinically severe peroxisomal disorders that includes the biogenesis disorder Zellweger syndrome and the single-enzyme defect D-bifunctional protein (D-BP) deficiency, are enlarged and significantly less abundant. We tested whether these features could be related to the known role of microtubules in...

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Source

Identifiers

PMID: 16449325
DOI: 10.1242/jcs.02776

Genes

PEX1
PEX13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Failure of microtubule-mediated peroxisome division and trafficking in disorders with reduced peroxisome abundance.PMID 16449325Read ↗

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