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Article

[A prevalent genetic variety of UDP-glycuronosyl transferase predicts high risk of irinotecan toxicity].

Medicina - 1 Jan 2007

Valsecchi Matias, Garberi Juan, Ferrandini Silvia, Berenguer Roxana, Trini Ernesto, Politi Pedro

Abstract excerpt

The advances in genetics and molecular biology have raised new areas in medicine, such as pharmacogenomics, which tries to predict drug responses and toxicities based on the individual genetic variability, describing the so called: pharmacogenomic syndromes. Oncology would find this development extremely useful because of the severe toxicity of chemotherapy. There are a lot of genetic loci under investigation for...

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Identifiers

PMID: 17408023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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