Germinal centres in T-cell-dependent antibody responses.

doi:10.1016/0167-5699(92)90199-H

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Article

Germinal centres in T-cell-dependent antibody responses.

Immunology today - 1 Jan 1992

Liu Y J, Johnson G D, Gordon J, MacLennan I C

Abstract excerpt

For more than a century follicles have been recognized as a site of intense cell proliferation and cell death. At last the significance of this activity is beginning to emerge: antigen-driven B-cell proliferation, somatic mutation, positive and negative selection, and memory and plasma cell devel...

Topics

Animals
Antibody Formation
B-Lymphocytes
Humans
Lymphoid Tissue
Mutation
Selection, Genetic
T-Lymphocytes

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