Article
PIN1 gene overexpression and beta-catenin gene mutation/expression in hepatocellular carcinoma and their significance.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban - 1 Feb 2007
Wang Hui, Zhang Jinxiang, Feng Wei, Zhang Shu, Liang Huifang, Wang Yang, Zheng Qichang, Li Zhuoya
Abstract excerpt
The evolution of hepatocellular carcinoma (HCC) is a compound process which involves many kinds of genes and transductional pathways. The expression of the peptidyl-proplyl-isomerase PIN1 gene, the mutation in exon 3 of beta-catenin and its correspondent abnormal expression and their roles in the hepatocellular carcinogeneisis were investigated. Among 29 pair cases of HCC and non-carcinoma tissues, the expression...
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