Article
Role of angiotensinogen gene polymorphism on Helicobacter pylori infection-related gastric cancer risk in Japanese.
Carcinogenesis - 1 Sept 2007
Sugimoto Mitsushige, Furuta Takahisa, Shirai Naohito, Kodaira Chise, Nishino Masafumi, Ikuma Mutsuhiro, Sugimura Haruhiko, Hishida Akira
Abstract excerpt
BACKGROUNDS AND AIMS: The renin-angiotensin (RA) system including angiotensinogen (AGT), angiotensin I and angiotensin II influences the regulation of cell proliferation, angiogenesis and inflammation. AGT-20 A/C polymorphism is associated with the plasma AGT and angiotensin II levels. The aim of this study was to clarify the association of AGT-20 A/C polymorphism with susceptibility to gastric cancer and peptic...
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