Article
Effects of interleukin-10 polymorphisms, Helicobacter pylori infection, and smoking on the risk of noncardia gastric cancer.
PloS one - 1 Jan 2012
Kim Jeongseon, Cho Young Ae, Choi Il Ju, Lee Yeon-Su, Kim Sook-Young, Shin Aesun, Cho Soo-Jeong, Kook Myeong-Cherl, Nam Ji Hyung, Ryu Keun Won, Lee Jun Ho, Kim Young-Woo
Abstract excerpt
OBJECTIVE: Both variations in the interleukin-10 (IL10) gene and environmental factors are thought to influence inflammation and gastric carcinogenesis. Therefore, we investigated the associations between IL10 polymorphisms, Helicobacter pylori (H. pylori) infection, and smoking in noncardia gastric carcinogenesis in Koreans. METHODS: We genotyped three promoter polymorphisms (-1082A>G, -819T>C, and -592 A>C) of...
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