Article
Cell specific internal translation efficiency of Epstein-Barr virus present in solid organ transplant patients.
Journal of medical virology - 1 May 2007
Isaksson Asa, Berggren Malin, Ekeland-Sjöberg Kerstin, Samuelsson Tore, Ricksten Anne
Abstract excerpt
The U leader exon in the 5' untranslated region of the Epstein-Barr virus nuclear antigen 1 (EBNA1) gene contains an internal ribosome entry site, the EBNA internal ribosome entry segment (IRES), which promotes cap-independent translation and increases the expression level of the EBNA1 protein. It was previously reported that immunosuppressed organ transplanted patients showed an alternatively spliced EBNA1...
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