Article
Determination of 24 minor red blood cell antigens for more than 2000 blood donors by high-throughput DNA analysis.
Transfusion - 1 Apr 2007
Hashmi Ghazala, Shariff Tasmia, Zhang Yi, Cristobal Joan, Chau Chiu, Seul Michael, Vissavajjhala Prabhakar, Baldwin Christopher, Hue-Roye Kim, Charles-Pierre Dalisay, Lomas-Francis Christine, Reid Marion E
Abstract excerpt
BACKGROUND: A "BeadChip" array permits reliable simultaneous DNA typing of single-nucleotide polymorphisms for minor blood groups. A high-throughput DNA analysis was studied as a routine method of phenotype prediction and software was developed to interpret and analyze the large volume of data points. STUDY DESIGN AND METHODS: DNA was extracted from whole blood of donors of known phenotypes and self-identified...
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