Article
Alcohol dehydrogenase type 1C (ADH1C) variants, alcohol consumption traits, HDL-cholesterol and risk of coronary heart disease in women and men: British Women's Heart and Health Study and Caerphilly cohorts.
Atherosclerosis - 1 Feb 2008
Ebrahim Shah, Lawlor Debbie A, Shlomo Yoav Ben, Timpson Nicholas, Harbord Roger, Christensen Mikkel, Baban Jamil, Kiessling Matt, Day Ian, Gaunt Tom, Davey Smith George
Abstract excerpt
The alcohol dehydrogenase 1C gene (ADH1C) gamma2gamma2 variant reportedly interacts with moderate alcohol consumption to increase HDL-cholesterol levels and reduce coronary heart disease (CHD). We undertook replication studies in two large population cohorts of women and men. 3234 women and 1313 men with relevant genotypic and phenotypic data from two prospective population cohorts were genotyped for ADH1C...
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