Article
Influence of alcohol dehydrogenase 1C polymorphism on the alcohol-cardiovascular disease association (from the Framingham Offspring Study).
The American journal of cardiology - 15 Jul 2005
Djoussé Luc, Levy Daniel, Herbert Alan G, Wilson Peter W F, D'Agostino Ralph B, Cupples L Adrienne, Karamohamed Samer, Ellison R Curtis
Abstract excerpt
Although moderate alcohol consumption is associated with a lower risk of cardiovascular disease (CVD), little is known of the effects of alcohol dehydrogenase 1C (ADH1C) polymorphism on the association between alcohol and CVD. We used data on 1,805 unrelated subjects in the Framingham Offspring Study to assess whether rs1693482 and rs698, 2 single nucleotide polymorphisms of the ADH1C gene, modify the relation...
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