Article
Alcohol consumption, genetic variants in alcohol deydrogenases, and risk of cardiovascular diseases: a prospective study and meta-analysis.
PloS one - 1 Jan 2012
Drogan Dagmar, Sheldrick Abigail J, Schütze Madlen, Knüppel Sven, Andersohn Frank, di Giuseppe Romina, Herrmann Bianca, Willich Stefan N, Garbe Edeltraut, Bergmann Manuela M, Boeing Heiner, Weikert Cornelia
Abstract excerpt
OBJECTIVE: First, to investigate and compare associations between alcohol consumption and variants in alcohol dehydrogenase (ADH) genes with incidence of cardiovascular diseases (CVD) in a large German cohort. Second, to quantitatively summarize available evidence of prospective studies on polymorphisms in ADH1B and ADH1C and CVD-risk. METHODS: We conducted a case-cohort study nested within the European...
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