Article
Correlation between single nucleotide polymorphisms and jejunal crypt cell apoptosis after whole body irradiation.
International journal of radiation biology - 1 Mar 2007
Iwata Masaru, Iwakawa Mayumi, Noda Shuhei, Ohta Toshie, Minfu Yang, Kimura Tomo, Shibuya Hitoshi, Imai Takashi
Abstract excerpt
PURPOSE: To identify loci concerned with radiosensitivity in a mouse model using single nucleotide polymorphism (SNP) markers. MATERIALS AND METHODS: We subjected 276 second filial generation (F2) mice descended from two inbred mouse strains, radiation-induced apoptosis sensitive C57BL/6JNrs (B6) and radiation-induced apoptosis resistant C3H/HeNrs (C3H), to 2.5 Gy whole-body irradiation. We quantified jejunal...
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